Colofac is an antispasmodic of myotropic action. Its main constituent is Mebeverine. It has a direct effect on the smooth muscles of the gastrointestinal tract. The preparation eliminates spasm without affecting normal intestinal motility. The preparation Colofac is prescribed for examinees who suffer from – colic, irritable bowel syndrome and functional disorders of the gastrointestinal tract.
Colic is a sharp, sudden pain, having the character fights. Colic appear while the spasm of the muscles of the peritoneum. Colic can be intestinal, liver (bile), kidney or pancreatic. The type of colic is determined by the place of the occurrence of spasmodic cramps. The causes of the colic depend on their type. Most often people suffer from intestinal colic, which appear due to the presence in the diet of fatty foods. Furthermore, these attacks are provoked sometimes by the fermentation and decay processes that cause intestinal gas and stretching. In rare cases, spasms can occur due to metal toxicity.
Irritable bowel syndrome (IBS) is a resistant complex of functional disorders which last not less than 12 weeks and are indicated by pains and / or malaise in the abdomen, which occur after defecation. This ailment has not less than 2 constant symptoms of bowel dysfunction: shifting in stool frequency and stool consistency and disorders of defecation (urgency, tenesmus, feeling of incomplete emptying of the bowel, additional efforts during defecation), mucus in the feces and flatulence. According to modern concepts, the disease is a biopsychosocial functional bowel disorder, which is based on the interaction of two main mechanisms: psychosocial intervention and sensorimotor dysfunction, which is the violation of visceral sensitivity and motor activity of the intestine.
Functional disorders of the gastrointestinal tract constitute a group of heterogeneous (different in nature and origin) of clinical conditions that manifest different symptoms from the gastrointestinal tract and are not accompanied by structural, metabolic or systemic changes. In the absence of the organic base diseases such disorders significantly reduce quality of life. These disorders include – IBS (thick and thin), functional flatulence, functional constipation, functional diarrhea and non-specific functional bowel disorders.